2003 JUL 1 - (NewsRx.com & NewsRx.net) -- CCR7 mRNA is linked to a higher risk of lymph node metastasis in nonsmall cell lung cancer.
"Tumor cell migration into the lymph nodes is an important aspect of cancer, yet little is known about the processes involved. CCR7 has been shown to play an important role in tumor cell migration and lymph node metastasis. The aim of our study was to evaluate the expression of CCR7 in nonsmall cell lung cancers (NSCLCs)," scientists in Japan report.
"We investigated CCR7 expression in 71 patients with NSCLC who underwent curative tumor resection, by means of RT-PCR and immunohistochemistry. CCR7 mRNA was expressed in 45 cases …
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